COPD and osteoporosis: links, risks, and treatment challenges

摘要: Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory airway associated with various systemic comorbidities including osteoporosis. Osteoporosis and its related fractures are common have significant impacts on quality of life even respiratory function in patients COPD. COPD-associated osteoporosis however extremely undertreated. Recent studies suggested that both decreased bone mineral density (BMD) impaired contribute to fragility, causing COPD patients. Various clinical risk factors patients, older age, emaciation, physical inactivity, vitamin D deficiency, also been described. It critically important for pulmonologists be aware the high prevalence evaluate them such fracture risks. Routine screening will enable physicians diagnose comorbid at an early stage give appropriate treatment prevent fracture, which may lead improved as well better long-term prognosis.