A new pH/organic modifier gradient RP HPLC method for convenient determination of lipophilicity and acidity of drugs as applied to established imidazoline agents.
作者： Paweł Wiczling , Antoni Nasal , Łukasz Kubik , Roman Kaliszan
DOI: 10.1016/J.EJPS.2012.04.021
关键词:
摘要: … RP HPLC is presented as a means of simultaneous determination of acidity and lipophilicity of a series of 26 imidazoline-like drugs. The … The simultaneously determined lipophilicity and …
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