Luteinizing hormone receptors and testosterone production in whole testes and purified Leydig cells from the mouse: differences among inbred strains.

作者: JOHN R. D. STALVEY , ANITA H. PAYNE

DOI: 10.1210/ENDO-112-5-1696

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摘要: Testicular and Leydig cell function were studied in four inbred strains of mice. Significant strain-related differences found the number LH receptors production testosterone vitro response to increasing concentrations human CG (hCG) by both decapsulated testes isolated cells. Maximal testicular was similar C57BL/10J C57BL/6J considerably less DBA/2J (DBA) C3H/HeJ strains, which similar. However, mice than all three other strains. The pattern maximal cells among that observed for whole testes, whereas per 106 least from DBA strain. When testis estimated dividing cells, it appar...

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