Intranasal dexmedetomidine in pediatrics: update of current knowledge.

摘要: Intranasal dexmedetomidine, although still off-label, recently boasted an increasing consensus for different uses, namely, in diagnostic non-painful procedures, painful procedures and surgical premedication. However, at present, there is no regarding indications, dosage timing administration. This article aims to provide a comprehensive literature analysis summarize the more recent evidence of research on pediatric intranasal effort better delineate usefulness limits each specific indication. In summary, available confirms efficacy safety dexmedetomidine Pharmacological profile various ages needs quality studies pharmacokinetic in-depth analysis.