The VEGF angiogenic switch of fibroblasts is regulated by MMP-7 from cancer cells.
作者： T-K Ito , G Ishii , H Chiba , A Ochiai
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摘要: … VA-13 fibroblasts promote angiogenesis in and … fibroblasts alone do not show significant angiogenesis. Treatment of VA-13 fibroblast supernatant with matrix metalloproteinase-7 (MMP-…
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Kalpna Gupta, Pankaj Gupta, Robert Wild, Sundaram Ramakrishnan, Robert P. Hebbel, Binding and displacement of vascular endothelial growth factor (VEGF) by thrombospondin: effect on human microvascular endothelial cell proliferation and angiogenesis. Angiogenesis. ,vol. 3, pp. 147- 158 ,(1999) , 10.1023/A:1009018702832
Peter Carmeliet, Rakesh K. Jain, Angiogenesis in cancer and other diseases Nature. ,vol. 407, pp. 249- 257 ,(2000) , 10.1038/35025220
Gabriele Bergers, Rolf Brekken, Gerald McMahon, Thiennu H. Vu, Takeshi Itoh, Kazuhiko Tamaki, Kazuhiko Tanzawa, Philip Thorpe, Shigeyoshi Itohara, Zena Werb, Douglas Hanahan, Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis Nature Cell Biology. ,vol. 2, pp. 737- 744 ,(2000) , 10.1038/35036374
Masanori Ii, Hiroyuki Yamamoto, Yasushi Adachi, Yumiko Maruyama, Yasuhisa Shinomura, Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis. Experimental Biology and Medicine. ,vol. 231, pp. 20- 27 ,(2006) , 10.1177/153537020623100103
Genichiro Ishii, Takafumi Sangai, Takashi Ito, Takahiro Hasebe, Yasushi Endoh, Hiroki Sasaki, Kenichi Harigaya, Atsushi Ochiai, In vivo andin vitro characterization of human fibroblasts recruited selectively into human cancer stroma International Journal of Cancer. ,vol. 117, pp. 212- 220 ,(2005) , 10.1002/IJC.21199
Christopher M. Overall, Oded Kleifeld, Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy Nature Reviews Cancer. ,vol. 6, pp. 227- 239 ,(2006) , 10.1038/NRC1821
Stela Gengrinovitch, Sheryl M. Greenberg, Tzafra Cohen, Hela Gitay-Goren, Patricia Rockwell, Theodore E. Maione, Ben-Zion Levi, Gera Neufeld, PLATELET FACTOR-4 INHIBITS THE MITOGENIC ACTIVITY OF VEGF121 AND VEGF165 USING SEVERAL CONCURRENT MECHANISMS Journal of Biological Chemistry. ,vol. 270, pp. 15059- 15065 ,(1995) , 10.1074/JBC.270.25.15059
Douglas Hanahan, Judah Folkman, Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis Cell. ,vol. 86, pp. 353- 364 ,(1996) , 10.1016/S0092-8674(00)80108-7
R. L. Kendall, K. A. Thomas, Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor Proceedings of the National Academy of Sciences of the United States of America. ,vol. 90, pp. 10705- 10709 ,(1993) , 10.1073/PNAS.90.22.10705
Bruce A Keyt, Lea T Berleau, Hung V Nguyen, Helen Chen, Henry Heinsohn, Richard Vandlen, Napoleone Ferrara, None, The Carboxyl-terminal Domain(111–165) of Vascular Endothelial Growth Factor Is Critical for Its Mitogenic Potency Journal of Biological Chemistry. ,vol. 271, pp. 7788- 7795 ,(1996) , 10.1074/JBC.271.13.7788