Molecular Biology for Oncologists

摘要: Part 1 Oncogenes: 1. What are cancer genes and how do they upset cell behaviour? (J. Yarnold). 2. Mechanisms of activation inactivation dominant oncogenes tumour suppressor (M. Stratton). 3. Approaches to proto-oncogene gene identification (H. Patterson). 4. Transgenic modelling recessive oncogene function (F.S. Pardo, E.V. Schmidt). 5. The BCL2 in clinical oncology Brada, M. Dyer). 6. Identification significance EGFR erbB2 overexpression (D.P. Hollywood, W.J. Gullick). 7. GTP-binding proteins Downward). 8. p53 human 9. Inherited predispositions - applications molecular biology (V.A. Murday). 1O. Multistage carcinogenesis (A.H. Wyllie). 11. Human papillomavirus cervical (R C. Davies, K.H. Vousden). 12. Cell-cycle control (A.M. Carr). 13. Differentiation (M.D. Mason). 2 Therapeutics: 14. Molecular aspects radiation sensitivity (C. Mort, T.J. McMillan). 15. Cells differ their susceptibility DNA damage induction ability repair it (S.J. Whitaker). 16. How cells damage? (G. Ross). 17. isolation (R. Cartwright, 18. Radiation-induced cytokines growth factors: cellular basis the modification Weichselbaum et al). 19. Chemotherapeutic drug-induced Brown, D. Bisset). 20. drug resistance (D. Hochhauser). 21. Antibody technology is being transformed (R.E. Hawkins, S.J. Russell). 22. Prospects for therapy (J.D. Harris, K. Sikora). 3 Gene Structure Techniques: 23. Introduction structure techniques Wooster). 24. Chromatin nuclear (A.B. Hassan, D.A. Jackson). 25. PCR revolution (R.A. Eeles, W. Warren, A. Stamps). 26. Techniques (P.J. Rocques).