Experimental studies on reproductive and perinatal effects of lead and cadmium
作者： Martina Piasek , Krista Kostial
DOI: 10.1108/09566169610123078
关键词:
摘要: Lead is a known reproductive toxicant in humans and animals. Data on cadmium effects are inconclusive, female animals lacking. More information the toxicokinetics toxicity of Pb Cd during period developing young needed. Experimental studies rats conducted laboratories Croatia USA separately as collaborative research show that or have function. Chronic subchronic oral exposure dams causes decreased pup weight survival, depressed serum progesterone concentration Cd‐exposed at term. No paternally mediated were found offspring. Organ accumulation was accompanied by changes essential element concentrations both dam foetus. Acute vivo vitro to had specific gonadal steroidogenesis males females. Proposes possible sites action steroidogenic pathway.
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