Model studies for brain dialysis.

作者: Ronald D. Johnson , Joseph B. Justice

DOI: 10.1016/0361-9230(83)90156-9

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摘要: Abstract A dialysis cannula suitable for perfusing deep brain structures in animals is described and characterized a series of model experiments. The effects flow rate, concentration, variations construction, barriers to diffusion pumping technique on the recovery tryptophan from aqueous solutions at 37°C were examined. 200 μm diameter gave good recoveries which varied about 8% 6 μl/min almost 90% 0.15 μl/min. Prepurification extracellular fluid by allows sample loop high performance liquid Chromatograph be incorporated outflow line direct injection dialysates.

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