Applications in Anatomic Pathology

作者: Jennifer L. Hunt , Sanja Dacic

DOI: 10.1007/978-0-387-89626-7_8

关键词:

摘要: Molecular testing in anatomic pathology is becoming increa-singly important, and molecular assays are used both diagnostically prognostically, particularly the workup of neoplasia for identification or subclassification certain infectious processes. Fresh frozen tissues optimal source DNA RNA to serve as template targeted analysis; however, archival formalin-fixed, paraffin-embedded tissue a frequently alternative clinical testing. Paraffin-embedded especially critical nucleic acid when pathological evaluation renders an unexpected diagnosis, it also provides advantage allowing analysis with correlation outcome.

参考文章(20)
Ralph H. Hruban, David Sidransky, Melvyn Tockman, Li Mao, Jay O. Boyle, Detection of Oncogene Mutations in Sputum Precedes Diagnosis of Lung Cancer Cancer Research. ,vol. 54, pp. 1634- 1637 ,(1994)
Aurélien de Reyniès, Valérie Boige, Gérard Milano, Jean Faivre, Pierre Laurent-Puig, KRAS mutation signature in colorectal tumors significantly overlaps with the cetuximab response signature. Journal of Clinical Oncology. ,vol. 26, pp. 2228- 2230 ,(2008) , 10.1200/JCO.2007.15.9186
William H. Westra, Robbert J. C. Slebos, G. Johan A. Offerhaus, Steven N. Goodman, Siegina G. Evers, Thomas W. Kensler, Frederic B. Askin, Sjoerd Rodenhuis, Ralph H. Hruban, K-ras oncogene activation in lung adenocarcinomas from former smokers. Evidence that K-ras mutations are an early and irreversible event in the development of adenocarcinoma of the lung Cancer. ,vol. 72, pp. 432- 438 ,(1993) , 10.1002/1097-0142(19930715)72:2<432::AID-CNCR2820720219>3.0.CO;2-#
Ze'ev Ronai, Marina S Yabubovskaya, Edith Zhang, Gennady A Belitsky, None, K-ras mutation in sputum of patients with or without lung cancer. Journal of Cellular Biochemistry. ,vol. 63, pp. 172- 176 ,(1996) , 10.1002/(SICI)1097-4644(1996)25+<172::AID-JCB24>3.0.CO;2-P
Lance A. Liotta, Emanuel F. Petricoin, Lu Charboneau, Nicole L. Simone, Cloud P. Paweletz, Cloud P. Paweletz, Cloud P. Paweletz, Laser Capture Microdissection: Beyond Functional Genomics to Proteomics Molecular Diagnosis. ,vol. 5, pp. 301- 307 ,(2000) , 10.1007/BF03262091
Sjoerd Rodenhuis, Robert J. C. Slebos, TherasOncogenes in Human Lung Cancer American Review of Respiratory Disease. ,vol. 142, pp. S27- S30 ,(1990) , 10.1164/AJRCCM/142.6_PT_2.S27
A D Chapman, K M Kerr, The association between atypical adenomatous hyperplasia and primary lung cancer. British Journal of Cancer. ,vol. 83, pp. 632- 636 ,(2000) , 10.1054/BJOC.2000.1317
Isam A. Eltoum, Gene P. Siegal, Andra R. Frost, Microdissection of Histologic Sections: Past, Present, and Future Advances in Anatomic Pathology. ,vol. 9, pp. 316- 322 ,(2002) , 10.1097/00125480-200209000-00006
Shioto Suzuki, Yoh Dobashi, Hiroyuki Sakurai, Keiichi Nishikawa, Mitsuhiko Hanawa, Akishi Ooi, Protein Overexpression and Gene Amplification of Epidermal Growth Factor Receptor in Nonsmall Cell Lung Carcinomas An Immunohistochemical and Fluorescence in Situ Hybridization Study Cancer. ,vol. 103, pp. 1265- 1273 ,(2005) , 10.1002/CNCR.20909
A Destro, P Bianchi, M Alloisio, L Laghi, S Di Gioia, A Malesci, U Cariboni, G Gribaudi, G Bulfamante, A Marchetti, S Bosari, M Infante, G Ravasi, M Roncalli, K-ras and p16INK4Aalterations in sputum of NSCLC patients and in heavy asymptomatic chronic smokers Lung Cancer. ,vol. 44, pp. 23- 32 ,(2004) , 10.1016/J.LUNGCAN.2003.10.002