作者: F. Gotoh , A. Koto , K. Tanaka , N. Suzuki , D. Uematsu
DOI: 10.1007/978-3-642-71787-1_23
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摘要: The observation of platelet microemboli in the retinal artery a patient with amaurosis fugax by Fisher [4] led to serious consideration role platelets transient ischemic attacks and also cerebrovascular diseases many investigators clinicians this field. Thus, functions patients have been subject much study discussion recent years [1]. Increased aggregability adhesiveness demonstrated stroke [6, 10, 13, 14]. Most these studies, however, were performed an vitro aggregation technique which has criticized as having limitations test for measurement vivo activity [2]. On other hand, it suggested that cerebral ischemia itself stimulates formation aggregates, could contribute process [3]. Thus pathogenesis occlusive may two stages: one cause thrombotic or embolic occlusion vessel, factor disturbance microcirculation after artery.