Cancer immunotherapy: accomplishments to date and future promise

摘要: Cancer remains a devastating disease as existing therapies are too often ineffective and toxicities remain unacceptably high. Immunotherapies for cancer offer the promise of specificity memory immune system against malignant cells to achieve durable cure with minimal toxicity. Beginning success bone marrow transplantation blood-borne cancers, more recent development monoclonal antibody therapeutics variety tumors, immunotherapies already among most successful class treatments cancer. Greater understanding immunoregulatory mechanisms improved techniques cell manipulation engineering have led new immunomodulatory approaches cell-based that generated great excitement within biomedical community. As these technologies continue improve, harnessing power developed, will play an increasingly important role in treatment Here, we review history discuss emerging immunotherapy hope translate into clinical reality.