Mycoplasma pulmonis Vsa proteins and polysaccharide modulate adherence to pulmonary epithelial cells.
作者： Jeffrey R. Bolland , Kevin Dybvig
DOI: 10.1111/J.1574-6968.2012.02551.X
关键词:
摘要: The Mycoplasma pulmonis Vsa proteins are a family of size- and phase-variable lipoproteins that shield the mycoplasmas from complement modulate attachment to abiotic surfaces. Mycoplasmas producing long protein hemadsorb poorly yet proficient at colonizing rats mice. effect length on epithelial cells has not been previously explored. We find independent isotype, with many tandem repeats adhere murine MLE-12 compared short Vsa. also mutants lacking EPS-I polysaccharide M. pulmonis exhibited decreased adherence cells, even though it shown such have an enhanced ability form biofilm.
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sci-hub.se 参考文章(29)
D. Yogev, R. Rosengarten, R. Watson-McKown, K.S. Wise, Molecular basis of Mycoplasma surface antigenic variation: a novel set of divergent genes undergo spontaneous mutation of periodic coding regions and 5' regulatory sequences. The EMBO Journal. ,vol. 10, pp. 4069- 4079 ,(1991) , 10.1002/J.1460-2075.1991.TB04983.X
Kevin Dybvig, Ping Lao, David S. Jordan, Warren L. Simmons, Fewer essential genes in mycoplasmas than previous studies suggest. Fems Microbiology Letters. ,vol. 311, pp. 51- 55 ,(2010) , 10.1111/J.1574-6968.2010.02078.X
W L Simmons, C Zuhua, J I Glass, J W Simecka, G H Cassell, H L Watson, Sequence analysis of the chromosomal region around and within the V-1-encoding gene of Mycoplasma pulmonis: evidence for DNA inversion as a mechanism for V-1 variation. Infection and Immunity. ,vol. 64, pp. 472- 479 ,(1996) , 10.1128/IAI.64.2.472-479.1996
P C Hu, A M Collier, J B Baseman, Interaction of virulent Mycoplasma pneumoniae with hamster tracheal organ cultures. Infection and Immunity. ,vol. 14, pp. 217- 224 ,(1976) , 10.1128/IAI.14.1.217-224.1976
I Lysnyansky, R Rosengarten, D Yogev, Phenotypic switching of variable surface lipoproteins in Mycoplasma bovis involves high-frequency chromosomal rearrangements. Journal of Bacteriology. ,vol. 178, pp. 5395- 5401 ,(1996) , 10.1128/JB.178.18.5395-5401.1996
Matthew S. Byrd, Irina Sadovskaya, Evgueny Vinogradov, Haiping Lu, April B. Sprinkle, Stephen H. Richardson, Luyan Ma, Brad Ralston, Matthew R. Parsek, Erin M. Anderson, Joseph S. Lam, Daniel J. Wozniak, Genetic and biochemical analyses of thePseudomonas aeruginosaPsl exopolysaccharide reveal overlapping roles for polysaccharide synthesis enzymes in Psl and LPS production Molecular Microbiology. ,vol. 73, pp. 622- 638 ,(2009) , 10.1111/J.1365-2958.2009.06795.X
Benjamin M. Hasselbring, Jarrat L. Jordan, Duncan C. Krause, Mutant Analysis Reveals a Specific Requirement for Protein P30 in Mycoplasma pneumoniae Gliding Motility Journal of Bacteriology. ,vol. 187, pp. 6281- 6289 ,(2005) , 10.1128/JB.187.18.6281-6289.2005
K A Wikenheiser, D K Vorbroker, W R Rice, J C Clark, C J Bachurski, H K Oie, J A Whitsett, Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice Proceedings of the National Academy of Sciences of the United States of America. ,vol. 90, pp. 11029- 11033 ,(1993) , 10.1073/PNAS.90.23.11029
Juliann Gumulak-Smith, Amy Teachman, Anh-Hue T. Tu, Jerry W. Simecka, J. Russell Lindsey, Kevin Dybvig, Variations in the surface proteins and restriction enzyme systems of Mycoplasma pulmonis in the respiratory tract of infected rats Molecular Microbiology. ,vol. 40, pp. 1037- 1044 ,(2001) , 10.1046/J.1365-2958.2001.02464.X
Warren L. Simmons, Kevin Dybvig, Mycoplasma biofilms ex vivo and in vivo. Fems Microbiology Letters. ,vol. 295, pp. 77- 81 ,(2009) , 10.1111/J.1574-6968.2009.01592.X