Motion effects on SUV and lesion volume in 3D and 4D PET scanning

摘要: To assess the effect of lesion motion and respiration rate on Standardised Uptake Value (SUV) ability 4D PET to restore any loss in SUV distortion volume two PET/CT systems. A Perspex phantom with four cylindrical reservoirs filled 18F-FDG was used this study. The cylinders measured 5, 10, 15, 20 mm diameter. GE Discovery STE8 (GE Medical Systems Milwaukee, WI) a Siemens Biograph 64/40 (Siemens Solutions, Erlangen, Germany) scanner acquire stationary un-gated scan phantom. Multiple 10 min list mode scans were acquired using Varian RPM camera Anzai Gating system camera. scanned at five different respiratory rates amplitudes sinusoidal fashion, 15 RPM/1 cm, RPM/2 RPM/4 30 cm 7.5 (RPM-respirations per minute). Each reconstructed into ten bins as an static image. SUVmax, SUVmean for all TrueD analysis software. With increasing movement SUVmax decreased increased smallest underestimated by up factor four. mostly recovered imaging regardless amount displacement. larger lesions showed better count recovery correction than smaller lesions. had no or volume. Un-gated moving decreases apparent small significantly overestimates volumes. scanning recovers most