Sialylation of epidermal growth factor receptor regulates receptor activity and chemosensitivity to gefitinib in colon cancer cells.

作者: Jung-Jin Park , Jae Youn Yi , Yeung Bae Jin , Yoon-Jin Lee , Jae-Seon Lee

DOI: 10.1016/J.BCP.2012.01.007

关键词:

摘要: … α2,6 sialylation of N-glycan, an action that … EGFR sialylation level, together with EGFR expression level and the presence of EGFR mutations, may be a reliable biomarker for anti-EGFR …

参考文章(50)
Jennifer S Lin, Elizabeth M Webber, Caitlyn A Senger, Rebecca S Holmes, Evelyn P Whitlock, Systematic review of pharmacogenetic testing for predicting clinical benefit to anti-EGFR therapy in metastatic colorectal cancer American Journal of Cancer Research. ,vol. 1, pp. 650- 662 ,(2011)
Emmanuelle J. Meuillet, Roger Kroes, Barbara Mania-Farnell, Joseph R. Moskal, Hirotaka Yamamoto, Jeffry Ferrari, Eric G. Bremer, Thomas G. Warner, Abdelhadi Rebbaa, David George, Sialidase gene transfection enhances epidermal growth factor receptor activity in an epidermoid carcinoma cell line, A431. Cancer Research. ,vol. 59, pp. 234- 240 ,(1999)
Louis Hornez, Anne Harduin-Lepers, Marie-Ange Recchi, Philippe Delannoy, Jean-Philippe Peyrat, Mohamed Hebbar, Multiplex Reverse Transcription Polymerase Chain Reaction Assessment of Sialyltransferase Expression in Human Breast Cancer Cancer Research. ,vol. 58, pp. 4066- 4070 ,(1998)
Muhammad W Saif, Colorectal cancer in review: the role of the EGFR pathway Expert Opinion on Investigational Drugs. ,vol. 19, pp. 357- 369 ,(2010) , 10.1517/13543781003593962
Takeshi Sato, Kiyoshi Furukawa, Matti Autero, Carl G. Gahmberg, Akira Kobata, Structural study of the sugar chains of human leukocyte common antigen CD45. Biochemistry. ,vol. 32, pp. 12694- 12704 ,(1993) , 10.1021/BI00210A019
Motoko Takahashi, Shunichi Yokoe, Michio Asahi, Seung Ho Lee, Wei Li, Daisuke Osumi, Eiji Miyoshi, Naoyuki Taniguchi, N-glycan of ErbB family plays a crucial role in dimer formation and tumor promotion. Biochimica et Biophysica Acta. ,vol. 1780, pp. 520- 524 ,(2008) , 10.1016/J.BBAGEN.2007.10.019