The effect of local application of mitomycin-C on the development of capsule around silicone implants in the breast: an experimental study in mice.

作者: Joanna Frangou , Maria Kanellaki

DOI: 10.1007/S002660010108

关键词:

摘要: In this experimental study on mice we try to prove that capsule formation around breast implants is considerably diminished after topical application of Mitomycin-C (MMC). MMC solution applied under the tissue or pectoralis major muscle, in pocket silicone implant and just before placing it. This a morphological connective formed implant, light electron microscope. Our results suggest it worthwhile working clinical trying prevent most common complication implants, contracture capsule.

参考文章(40)
Hiroshi Ando, Tadayoshi Ido, Yuko Kawai, Tetsuya Yamamoto, Yoshiaki Kitazawa, Inhibition of corneal epithelial wound healing. A comparative study of mitomycin C and 5-fluorouracil. Ophthalmology. ,vol. 99, pp. 1809- 1814 ,(1992) , 10.1016/S0161-6420(92)31721-X
Boyd R. Burkhardt, Capsular contracture: hard breasts, soft data. Clinics in Plastic Surgery. ,vol. 15, pp. 521- 532 ,(1988) , 10.1016/S0094-1298(20)31387-0
Melvin Willard Stromberg, Rudolf Hebel, Anatomy and embryology of the laboratory rat Published in <b>1986</b> in Wörthsee by Biomed. ,(1986)
Eunice Chace Greene, Anatomy of the rat ,(1935)
Klein Ce, Trautmann A, Bröcker Eb, Krohne G, Human Mast Cells Augment Fibroblast Proliferation by Heterotypic Cell-Cell Adhesion and Action of IL-4 Journal of Immunology. ,vol. 160, pp. 5053- 5057 ,(1998)
HUGH D. PETERSON, GLENN B. BURT, The role of steroids in prevention of circumferential capsular scarring in augmentation mammaplasty. Plastic and Reconstructive Surgery. ,vol. 54, pp. 28- 30 ,(1974) , 10.1097/00006534-197407000-00003
Kazuhide Kawase, Hiromi Matsushita, Tetsuya Yamamoto, Yoshiaki Kitazawa, Mitomycin Concentration in Rabbit and Human Ocular Tissues after Topical Administration Ophthalmology. ,vol. 99, pp. 203- 207 ,(1992) , 10.1016/S0161-6420(92)31992-X
Robert M. Oneal, Louis C. Argenta, Late side effects related to inflatable breast prostheses containing soluble steroids. Plastic and Reconstructive Surgery. ,vol. 69, pp. 641- 645 ,(1982) , 10.1097/00006534-198204000-00012