A metabolomic study on the biological effects of metal pollutions in oysters Crassostrea sikamea

作者: Chenglong Ji , Qing Wang , Huifeng Wu , Qiaoguo Tan , Wen-Xiong Wang

DOI: 10.1016/J.MARPOLBUL.2015.11.037

关键词:

摘要: Metal pollution has become a great threat to organisms in the estuaries South China. In present study, oysters Crassostrea sikamea were collected from one clean (Jiuzhen) and five metal polluted sites (Baijiao, Fugong, Gongqian, Jinshan Songyu). The tissue concentrations indicated that by several metals, including Cr, Ni, Co, Cu, Zn, Ag, Cd Pb with different patterns. Especially, Cu Zn major contaminants Baijiao, Fugong sites. metabolic responses C. pollutions BJ, FG, JS SY induced disturbances osmotic regulation energy metabolism via pathways. However, GQ site mainly influenced sikamea. This study demonstrates NMR-based metabolomics is useful characterize pollution.

参考文章(27)
Fengjie Liu, Wen-Xiong Wang, Proteome pattern in oysters as a diagnostic tool for metal pollution Journal of Hazardous Materials. ,vol. 239-240, pp. 241- 248 ,(2012) , 10.1016/J.JHAZMAT.2012.08.069
Eduardo Alves de Almeida, Sayuri Miyamoto, Afonso Celso Dias Bainy, Marisa Helena Gennari de Medeiros, Paolo Di Mascio, Protective effect of phospholipid hydroperoxide glutathione peroxidase (PHGPx) against lipid peroxidation in mussels Perna perna exposed to different metals Marine Pollution Bulletin. ,vol. 49, pp. 386- 392 ,(2004) , 10.1016/J.MARPOLBUL.2004.02.020
Eduarda M Santos, Jonathan S Ball, Tim D Williams, Huifeng Wu, Fernando Ortega, Ronny Van Aerle, Ioanna Katsiadaki, Francesco Falciani, Mark R Viant, James K Chipman, Charles R Tyler, None, Identifying health impacts of exposure to copper using transcriptomics and metabolomics in a fish model. Environmental Science & Technology. ,vol. 44, pp. 820- 826 ,(2010) , 10.1021/ES902558K
Mark R. Viant, Eric S. Rosenblum, Ronald S. Tjeerdema, NMR-Based Metabolomics: A Powerful Approach for Characterizing the Effects of Environmental Stressors on Organism Health Environmental Science & Technology. ,vol. 37, pp. 4982- 4989 ,(2003) , 10.1021/ES034281X
R. A. Graham, W. R. Ellington, Anaerobic aspartate metabolism and the formation of alanine in molluscan cardiac muscle: A13C Nmr study Journal of Experimental Zoology. ,vol. 236, pp. 365- 370 ,(1985) , 10.1002/JEZ.1402360315
Thomas M Stokes, J Awapara, Alanine and succinate as end-products of glucose degradation in the clam Rangia cuneata Comparative Biochemistry and Physiology. ,vol. 25, pp. 883- 892 ,(1968) , 10.1016/0010-406X(68)90576-8
Jianghua Feng, Jinquan Li, Huifeng Wu, Zhong Chen, Metabolic responses of HeLa cells to silica nanoparticles by NMR-based metabolomic analyses Metabolomics. ,vol. 9, pp. 874- 886 ,(2013) , 10.1007/S11306-013-0499-8
Salvatore Fasulo, Francesco Iacono, Tiziana Cappello, Carmelo Corsaro, Maria Maisano, Alessia D'Agata, Alessia Giannetto, Elena De Domenico, Vincenzo Parrino, Giuseppe Lo Paro, Angela Mauceri, Metabolomic investigation of Mytilus galloprovincialis (Lamarck 1819) caged in aquatic environments. Ecotoxicology and Environmental Safety. ,vol. 84, pp. 139- 146 ,(2012) , 10.1016/J.ECOENV.2012.07.001