Children with macrocrania: clinical and imaging predictors of disorders requiring surgery.

作者: David Zurakowski , L. Santiago Medina , Kieran Frawley , Kerry R. Crone , Antonius J.C. DeGrauw

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摘要: BACKGROUND AND PURPOSE: Macrocrania is a common pediatric clinical condition affecting up to 5% of the population. The purpose this study was determine and imaging predictors that are useful in differentiation disorders requiring surgical treatment from those can be treated medically children with macrocrania. METHODS: In 3-year 7-month retrospective study, 88 patients (median age, 8 months; interquartile range, 5−13 months) macrocrania no known underlying neurologic disorder underwent brain (sonography, n = 36; CT, 31; MR 21). conducted tertiary care referral center. Clinical data were correlated final diagnosis by means logistic regression receiver operating characteristic curves. RESULTS: Sixteen (18%) had surgery: communicating hydrocephalus, 7; noncommunicating 3; hemorrhagic subdural collections, neoplasm, 1; encysted cavum septi pellucidi, vein Galen malformation, 1. surgery included vomiting ( P .007), labor instrumentation .026), developmental delay .008), abnormal findings .028). Imaging focal space-occupying lesion .09). An increase number highly an increased risk CONCLUSION: Baseline neuroimaging indicated for because combination has best diagnostic performance determining need versus nonsurgical management.

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