Hubungan kadar leptin serum dengan derajat rinitis alergi
作者： Ahmad Dian Wahyudiono , Endang Retnoningsih , Pudji Rahaju
关键词:
摘要: Background: Allergic rhinitis is a global health problem that could impair the patient’s quality of life. Recent studies had showed role leptin, a hormone produced by adipose tissue, on sensitization process which can increase serum level B cells and IgE. Purpose: To define relationship between leptin with degree allergic based ARIA VAS. Methods: This study involved 38 subjects cross sectional design. Statistical analysis included t-test, logistic regression Kruskal-Wallis. Results: This has correlation (p<0.05), specifically intensity but not VAS. Conclusion: Serum severity symptoms. Controlling be considered as promotion for patient rhinitis. Further research focusing controlling symptoms recommended. Keywords: allergic rhinitis, level, rhinitis Abstrak : Latar belakang: Rinitis alergi merupakan masalah kesehatan dan dapat mengganggu kualitas hidup penderitanya. Beberapa penelitian telah menunjukkan peran leptin, hormon yang diproduksi oleh jaringan lemak, pada proses sensitisasi ditandai dengan kemampuan meningkatkan sel Tujuan: Penelitian ini bertujuan mengetahui hubungan kadar derajat rinitis alergi. Metode: Penelitian melibatkan subjek desain potong lintang untuk penderita . Analisis statistik digunakan adalah uji t, regresi Kruskal-Wallis. Hasil: bahwa berhubungan berdasarkan (p<0,05) khususnya intensitas keluhannya (p<0,05), namun tidak Kesimpulan: Kadar terutama keluhan bukan beratnya keluhan. Pengendalian dipertimbangkan sebagai upaya memperbaiki alergi. lebih lanjut menekankan pengendalian disarankan mengendalikan Kata kunci: rinitis alergi, serum,
perhati-kl.or.id 参考文章(18)
Robert Naclerio, David Chiu, Elliot, Allergic Rhinitis ,(2001)
P. J. Bousquet, C. Combescure, F. Neukirch, J. M. Klossek, H. Méchin, J.-P. Daures, J. Bousquet, Visual analog scales can assess the severity of rhinitis graded according to ARIA guidelines. Allergy. ,vol. 62, pp. 367- 372 ,(2007) , 10.1111/J.1398-9995.2006.01276.X
Christos S. Mantzoros, The Role of Leptin in Human Obesity and Disease: A Review of Current Evidence Annals of Internal Medicine. ,vol. 130, pp. 671- 680 ,(1999) , 10.7326/0003-4819-130-8-199904200-00014
Sara Miri, Reza Farid, Hedayat Akbari, Reza Amin, Prevalence of allergic rhinitis and nasal smear eosinophilia in 11- to 15 yr-old children in Shiraz Pediatric Allergy and Immunology. ,vol. 17, pp. 519- 523 ,(2006) , 10.1111/J.1399-3038.2006.00424.X
Cynthia M. Visness, Stephanie J. London, Julie L. Daniels, Jay S. Kaufman, Karin B. Yeatts, Anna-Maria Siega-Riz, Andrew H. Liu, Agustin Calatroni, Darryl C. Zeldin, Association of obesity with IgE levels and allergy symptoms in children and adolescents: results from the National Health and Nutrition Examination Survey 2005-2006. The Journal of Allergy and Clinical Immunology. ,vol. 123, pp. 1163- 1169 ,(2009) , 10.1016/J.JACI.2008.12.1126
C BERGERON, L BOULET, Q HAMID, Obesity, allergy and immunology. The Journal of Allergy and Clinical Immunology. ,vol. 115, pp. 1102- 1104 ,(2005) , 10.1016/J.JACI.2005.03.018
Harun Alrasyid, Alexandra McManus, Dominic Mallon, Claire Nicholson, Elevated Body Mass Index is associated with severity of Allergic Rhinitis: Results from a cross sectional study Australasian Medical Journal. ,vol. 1, ,(2008) , 10.4066/AMJ.2008.30
A V Irei, K Takahashi, Duc Son N T Le, P T N Ha, N T K Hung, D Kunii, T Sakai, T Matoba, S Yamamoto, Obesity is associated with increased risk of allergy in Vietnamese adolescents. European Journal of Clinical Nutrition. ,vol. 59, pp. 571- 577 ,(2005) , 10.1038/SJ.EJCN.1602120
Murat Ünal, Gülçin Eskandari, Necati Muşlu, Yavuz Selim Pata, Yücel Akbaş, Serum leptin levels in patients with allergic rhinitis. Otolaryngology-Head and Neck Surgery. ,vol. 134, pp. 331- 333 ,(2006) , 10.1016/J.OTOHNS.2005.11.021
Jasmien Taildeman, Claudina A. Pérez-Novo, Isabelle Rottiers, Liesbeth Ferdinande, Anouk Waeytens, Veerle De Colvenaer, Claus Bachert, Pieter Demetter, Wim Waelput, Katleen Braet, Claude A. Cuvelier, Human mast cells express leptin and leptin receptors Histochemistry and Cell Biology. ,vol. 131, pp. 703- 711 ,(2009) , 10.1007/S00418-009-0575-3