Adverse events related to olanzapine.

摘要: Olanzapine, a serotonin-dopamine receptor antagonist, is one of the novel atypical antipsychotics that effective against positive and negative symptoms schizophrenia with significantly fewer treatment-emergent extrapyramidal less akathisia associated traditional antipsychotics. Compared agents, olanzapine shows only few adverse events such as dry mouth, sedation, increase in appetite. risperidone, causes greater increases weight gain body mass index but hyperprolactinemia. Transient, non-dose-dependent, asymptomatic elevations liver enzymes have also been noted olanzapine-treated patients. Because comparative efficacy improved side effect profiles antipsychotics, consideration should be given to using newer agents preferred treatment for related psychoses.