Minireview: Prolactin Regulation of Adult Stem Cells
作者： Lucila Sackmann-Sala , Jacques-Emmanuel Guidotti , Vincent Goffin
DOI: 10.1210/ME.2015-1022
关键词:
摘要: Adult stem/progenitor cells are found in many tissues, where their primary role is to maintain homeostasis. Recent studies have evaluated the regulation of adult by prolactin various target tissues or cell types, including mammary gland, prostate, brain, bone marrow, hair follicle, and colon cancer cells. Depending on tissue, can either stem quiescence or, contrast, promote expansion push progeny towards differentiation. In instances, whether these effects direct involve paracrine regulators remains debated. This minireview aims overview current knowledge field.
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