The Effect of Ipomoea batatas (Caiapo) on Glucose Metabolism and Serum Cholesterol in Patients With Type 2 Diabetes A randomized study

作者: B. H. Ludvik , K. Mahdjoobian , W. Waldhaeusl , A. Hofer , R. Prager

DOI: 10.2337/DIACARE.25.1.239

关键词:

摘要: There is considerable and growing interest in neutraceutical products for the treatment of diabetes (1). Recently, it has been shown that caiapo, extract white-skinned sweet potato ( Ipomoea batatas ), improves glycemic control rodents by reducing insulin resistance (2). The aim our study was to assess effect caiapo on glucose metabolism its tolerability mode action male Caucasian type 2 diabetic patients a randomized, double-blind prospective parallel groups controlled with placebo. A total 18 (age: 58 ± 8 years; weight: 88 3 kg; BMI: 27.7 2.7 kg/m2; means SEM) treated diet alone were randomized receive placebo or (low dose) 4 g (high (four tablets each containing 168 336 mg powdered [ I. ], respectively) before breakfast, lunch, dinner 6 weeks. protocol approved Ethics Committee University Vienna, informed consent obtained from all inclusion into study. Safety parameters (hematology blood chemistry, including hepatic enzymes urinanalysis) at end study, asked report any adverse events. Patients seen weekly during 6-week trial, fasting measured. Each subject underwent frequently sampled intravenous tolerance test (FSIGT) …

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