Mycoplasma gallisepticum: Influence of cell invasiveness on the outcome of experimental infection in chickens

摘要: Recently we have shown that a low (Rlow) and high laboratory passage (Rhigh) of the poultry pathogen Mycoplasma gallisepticum prototype strain R differ markedly in their capability to invade non-phagocytic eukaryotic cells. In present study infection traits these two mycoplasma passages were compared an vivo setting. After aerosol inoculation chickens, M. was re-isolated from inner organs birds infected with Rlow, whereas no recovered Rhigh. These results indicate populations derived capacity cross mucosal barrier suggest cell invasion may play major role observed systemic spreading its chicken host.