DEVELOPMENT OF A WHOLE BODY MAGNETIC RESONANCE IMAGING PROTOCOL IN NORMAL DOGS AND CANINE CANCER PATIENTS

摘要: Whole body magnetic resonance imaging (whole MR imaging) could potentially provide accurate cancer staging as a single modality. This study was done to develop whole protocol for 1.5T instrument using four normal Beagle dogs (Phase 1) and then assess the protocol's feasibility in cancer-bearing II). In Phase I, anesthetized were placed dorsal recumbency with limbs flexed along torso. T1, T2, short tau inversion recovery sequences acquired by spin echo or fast echo, also more rapid shot gradient pulse sequences. Three large overlapping fields of view (FOV) used visualize entire sagittal planes compared. Relative examination time, image quality, organ visibility signal intensity evaluated. I results establish that balanced quality time. II, on 10 cancer. Examination times 60-75 min. Image sufficient all known lesions be visualized, including mass lesions, pulmonary infiltrate, lymphadenomegaly. Skeletal detail neoplastic appendicular skeleton, yet it suboptimal because FOV use coil. Additional modifications continued technological improvements will further increase its potential veterinary staging.