Modification of altered ankle motor control after stroke using focal application of botulinum toxin type A.

摘要: Abstract Study design Blinded, placebo-controlled, prospective clinical trial. Purpose To examine the effects of botulinum toxin type A (BTX-A) injections into plantar flexor muscles in stroke patients with equinovarus gait. Subjects 15 post-stroke and 10 matched neurologically intact subjects. Methods Modified Ashworth Scale (MAS) Fugl–Meyer assessment physical function scale scores along surface EMG collected before up to 12 weeks after BTX-A muscle motor points Saline placebo were performed a subset subject group. Results MAS decreased at 4, 8 but F–M did not improve until post injection. Multi-muscle patterns showed return volitional dorsiflexor activity 11 decrease antagonistic distant coactivation all one 15. Conclusions is effective reducing activation that impedes dorsiflexion.