Interaction of the T cell receptor with bacterial superantigens

摘要: Abstract Bacterial toxin superantigens bind to MHC class II molecules and activate a large proportion of T cells through direct interaction with the cell receptor (TCR). The toxin: TCR involves specific recognition between β-chain variable region toxin. Although complete αβ is required for activation cells, studies using purified soluble have shown that it alone sufficient binding complex. regions Vβ enterotoxin involved in been determined.