作者: Franz H. Messerli , Roland Schmieder
DOI: 10.2165/00003495-198600314-00023
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摘要: The heart adapts to increasing afterload, such as that which occurs in arterial hypertension, with an increase wall thickness order bring stress back normal. As a consequence, concentric left ventricular hypertrophy ensues. Hypertension well advancing age has been shown be associated posterior thickness. Accordingly, the prevalence of becomes very high elderly and may occur more than 50% hypertensive patients. Left is not merely physiological process serving compensate for increased afterload. Framingham study indicated patients are at risk sudden death other cardiovascular morbidity mortality. 5 6 times higher those without, regardless levels pressure. By Holter monitoring these it have premature contractions 40 50 without hypertrophy. In addition, rated substantially regard Lown’s classes without. These data indicate common, particularly elderly, predisposes ectopy, grade arrhythmias, death. Clearly, considerations taken into account when selecting antihypertensive therapy inasmuch hypokalaemia, hypomagnesaemia, electrolyte shifts predisposing arrhythmias must scrupulously avoided.