Real-time Intraoperative Computed Tomography Assessment of Quality of Permanent Interstitial Seed Implantation for Prostate Cancer
作者： Michael J Zelefsky , Mick Worman , Gilad N Cohen , Xin Pei , Marisa Kollmeier
DOI: 10.1016/J.UROLOGY.2010.01.067
关键词:
摘要: Objectives To evaluate the use of real-time kilovoltage cone-beam computed tomography (CBCT) during prostate brachytherapy for intraoperative dosimetric assessment and correcting deficient dose regions. Methods A total 20 patients were evaluated intraoperatively with a mobile CBCT unit immediately after implantation while still anesthetized. The source detector system was enclosed in circular CT-like geometry bore that accommodates lithotomy position. After seed deposition, scans obtained. dosimetry compared standard postimplantation CT-based assessment. In 8 patients, deposited seeds localized frame reference registered to transrectal ultrasound images. With this information, second plan generated ascertain whether additional needed achieve planned prescription dose. final scan Results mean differences between parameters from postimplant CT Conclusions Intraoperative evaluation permanent before anesthesia reversal is feasible might avert misadministration delivery. measurements using dependable correlated well diagnostic findings.
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