NODAPA-OH and NODAPA-(NCS)n: synthesis, 68Ga-radiolabelling and in vitro characterisation of novel versatile bifunctional chelators for molecular imaging
作者： Patrick J. Riss , Carsten Kroll , Verena Nagel , Frank Rösch
DOI: 10.1016/J.BMCL.2008.09.054
关键词:
摘要: This report concerns synthesis, (68)Ga-radiolabelling and stability data of 1,4,7-triazacyclononane-1,4-diacetic acid-7-p-isothio-cyanatophenyl-acetic acid (NODAPA-NCS), 1,4,7-triazacyclononane-1-acetic acid-4,7-di-p-isothiocyanatophenyl-acetic (NODAPA-(NCS)(2)) acid-7-p-hydroxyphenyl-acetic (NODAPA-OH), versatile bifunctional chelators with potential for molecular imaging. Protein binding exemplified conjugation are also reported.
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