Lymphocyte transformation by phytohaemagglutinin (PHA) and purified protein derivative (PPD) in primary biliary cirrhosis. Evidence of serum inhibitory factors

摘要: Factors inhibitory to lymphocyte transformation in vitro by PHA and PPD have been demonstrated the majority of sera from patients with primary biliary cirrhosis. These factors inhibited response both autologous lymphocytes, `reference' lymphocytes which were obtained a single donor. `Reference' was significantly less when cultured cirrhosis control subjects than AB serum.