The sentinel lymph node procedure for patients with preoperative diagnosis of ductal carcinoma in situ: risk factors for unsuspected invasive disease and for metastatic sentinel lymph nodes.

摘要: Summary Background:  Occult invasive disease could be found at definitive histology in patients initially diagnosed with large ductal carcinoma situ (DCIS). Sentinel lymph node (SLN) biopsy is a reliable and minimally procedure providing axillary information avoiding second operation this particular group of patients. The aim our study was to assess the value SLN DCIS who are highest risk for being upstaged carcinoma. Patients methods:  included 195 upon initial core undergoing biopsy. Many features were correlated presence unsuspected positive using univariate multivariate analyses. Results:  Of 110 pure DCIS, seven (6%) had metastatic node; 31 (16%) have final histology. Univariate analysis predictors showed that having preoperative indicated microinvasion (DCISM) or higher after histological examination operative specimen. histology, (22%) shows diffuse requiring mastectomy main factor metastasis. Conclusion:  There no real predictive factors an diagnosis DCISM. Our supports DCISM mastectomy.