Age-correlated stress resistance improves fitness of yeast: support from agent-based simulations.
作者： Ferdi L Hellweger , Neil D Fredrick , John A Berges
关键词:
摘要: Background Resistance to stress is often heterogeneous among individuals within a population, which helps protect against intermittent (bet hedging). This also the case for heat shock resistance in budding yeast Saccharomyces cerevisiae. Interestingly, appears be continuously distributed (vs. binary, switch-like) and correlated with replicative age random). Older, slower-growing cells are more resistant than younger, faster-growing ones. Is there fitness benefit age-correlated resistance?
biomedcentral.com
springer.com
paperity.org参考文章(55)
Sara L. Holland, Tom Reader, Paul S. Dyer, Simon V. Avery, Phenotypic heterogeneity is a selected trait in natural yeast populations subject to environmental stress. Environmental Microbiology. ,vol. 16, pp. 1729- 1740 ,(2014) , 10.1111/1462-2920.12243
Bas Teusink, Jutta Passarge, Corinne A. Reijenga, Eugenia Esgalhado, Coen C. van der Weijden, Mike Schepper, Michael C. Walsh, Barbara M. Bakker, Karel van Dam, Hans V. Westerhoff, Jacky L. Snoep, Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes? Testing biochemistry. FEBS Journal. ,vol. 267, pp. 5313- 5329 ,(2000) , 10.1046/J.1432-1327.2000.01527.X
Edward R. Sumner, Angela M. Avery, John E. Houghton, R. Adrian Robins, Simon V. Avery, Cell cycle‐ and age‐dependent activation of Sod1p drives the formation of stress resistant cell subpopulations within clonal yeast cultures Molecular Microbiology. ,vol. 50, pp. 857- 870 ,(2003) , 10.1046/J.1365-2958.2003.03715.X
Anita Panek, Function of trehalose in Baker's yeast (Saccharomyces cerevisiae) Archives of Biochemistry and Biophysics. ,vol. 100, pp. 422- 425 ,(1963) , 10.1016/0003-9861(63)90107-3
J. Winderickx, J. H. de Winde, M. Crauwels, A. Hino, S. Hohmann, P. Van Dijck, J. M. Thevelein, Regulation of genes encoding subunits of the trehalose synthase complex inSaccharomyces cerevisiae: novel variations of STRE-mediated transcription control? Molecular and General Genetics MGG. ,vol. 252, pp. 470- 482 ,(1996) , 10.1007/BF02173013
Sasha F Levy, Naomi Ziv, Mark L Siegal, None, Bet Hedging in Yeast by Heterogeneous, Age-Correlated Expression of a Stress Protectant PLoS Biology. ,vol. 10, pp. e1001325- ,(2012) , 10.1371/JOURNAL.PBIO.1001325
Edda Klipp, Bodil Nordlander, Roland Krüger, Peter Gennemark, Stefan Hohmann, Integrative model of the response of yeast to osmotic shock Nature Biotechnology. ,vol. 23, pp. 975- 982 ,(2005) , 10.1038/NBT1114
J. Li, R. Min, F. J. Vizeacoumar, K. Jin, X. Xin, Z. Zhang, Exploiting the determinants of stochastic gene expression in Saccharomyces cerevisiae for genome-wide prediction of expression noise Proceedings of the National Academy of Sciences of the United States of America. ,vol. 107, pp. 10472- 10477 ,(2010) , 10.1073/PNAS.0914302107
Kenneth D. Jones, Dhinakar S. Kompala, Cybernetic model of the growth dynamics of Saccharomyces cerevisiae in batch and continuous cultures. Journal of Biotechnology. ,vol. 71, pp. 105- 131 ,(1999) , 10.1016/S0168-1656(99)00017-6
H.R. Hirsch, Accumulation of a senescence factor in yeast cells. Experimental Gerontology. ,vol. 28, pp. 195- 204 ,(1993) , 10.1016/0531-5565(93)90008-2