Qualitative and quantitative image analysis of CT and MR imaging in patients with neuroendocrine liver metastases in comparison to 68Ga-DOTATOC PET
作者： Frederik L. Giesel , Paul Flechsig , Christian M. Zechmann , Julian Schreiweis , Clemens Kratochwil
DOI: 10.1016/J.EJRAD.2015.04.009
关键词:
摘要: Abstract Purpose To compare lesion conspicuity in patients with liver metastases arising from gastroenteropancreatic neuroendocrine tumors (GEP-NETs) using MRI, PET and CT. Materials methods 16 GEP-NETs were evaluated non-contrast contrast-enhanced (CE) MRI Gd-EOB-DTPA CE- 68 Ga-DOTATOC PET. Quantitative analyses performed by two blinded readers ROI-analyses quantifying contrast ratios (CR) between normal liver-tissue GEP-NET-metastases. Qualitative evaluating primary visibility spatial detectability of all lesions. Results 103 the same detected on modalities. Qualitatively, was superior CE-MRI imaging compared to MR-sequences (T2, DWI, fl2D, fl3D), as well arterial- portal-venous phase Concerning lesions, other The quantitative ROI-analysis demonstrated improved CR for DWI ( p PET/CT Conclusions Anatomic non fl2D-and fl3D-sequences combination molecular modality is optimal assessment lesions GEP-NET-patients. Even though sufficient detect quantify daily routine, especially DW-Imaging.
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