Prevalence of hepatitis E virus infection in West Bengal, India: a hospital-based study
作者： Nidhi S. Chandra , Durbadal Ojha , Sanjoy Chatterjee , Debprasad Chattopadhyay
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摘要: India is an endemic zone for hepatitis E virus (HEV), which associated with both epidemic and sporadic infections. In West Bengal, only two outbreaks have been studied to date. However, cases of HEV infection also occur during inter-epidemic periods. The aim this hospital-based study was detect the prevalence in patients acute India. Blood samples clinical information were collected from 285 sexes different ages viral (AVH) at Calcutta Medical College, Kolkata, a tertiary-care centre. Samples tested B (HBV) surface antigen, anti-hepatitis C antibodies, A IgM anti-HEV antibodies (IgM IgG) by ELISA. Only those AVH who their first week illness negative all hepatotropic RNA reverse transcriptase nested PCR. identified as most common cause (41.8% patients), followed HBV (21.4%), (17.2%) (4.6%). Co-infections more than one found 22 patients, HBV-HEV co-infection (3.8%). 14.7% had no marker. To best our knowledge, documented epidemiological state India, indicating that infection.
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