The improved resistance of PDMS to pressure-induced deformation and chemical solvent swelling for microfluidic devices

摘要: Graphical abstractDisplay Omitted We combined and modified previously isolated treatment processes to improve the properties of PDMS.The improved PDMS shows 860% less deformation compared regular at same pressure conditions.Chemical swelling is also when are in contact with toluene.Rhodamine B diffuses into much than PDMS. present a fabrication technique that increases resistance under driven flow chemical solvents without use any foreign materials. This achieved by enhancing material coupling two processes. First, weight ratio prepolymer curing agent was increased from 10:1 5:1, latter showing 20% pressurized conditions. Second, cured thermally aged 200?C for few hours, resulting 140% chip The benefit nonlinear effect on improvement show enhanced standard chip. microchannels quantified using fluorescence microscopy. compatibility nonpolar explored quantifying due toluene absorption brightfield imaging microchannel. showed 10% against 55% permeable small hydrophobic molecule rhodamine (RhB), as epi-fluorescence microscopy absorbed dye. surface treated certainly beneficial microfluidic applications this common soft lithography material.