Prognostic and predictive biomarkers in adult and pediatric gliomas: toward personalized treatment

摘要: It is increasingly clear that both adult and paediatric glial tumour entities represent collections of neoplastic lesions, each with individual pathological molecular events treatment responses. In this review we discuss the current prognostic biomarkers validated for clinical use or future validity gliomas. Accurate prognostication crucial managing patients as treatments may be associated high morbidity benefits risk interventions must judged by treating clinicians. We also predictive which become clinically relevant development targeted therapies