Villoglandular papillary adenocarcinoma of the uterine cervix responding to neoadjuvant chemotherapy with docetaxel and cisplatin: a case report

作者: N. NAGAI , E. HIRATA , T. KUSUDA , K. MUKAI , K. ARIHIRO

DOI: 10.1111/J.1525-1438.2005.00186.X

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摘要: Villoglandular papillary adenocarcinoma (VGPA) of the uterine cervix is a rare neoplasm, and its treatment has rarely been reported. We report patient with VGPA stage IIA responding to neoadjuvant chemotherapy docetaxel (60 mg/m2 as an intravenous infusion) cisplatin (70 intra-arterial infusion). At 3 weeks after completing one course this regimen, tumor size was reduced from 5.3 x 4.0 cm 2.0 (81.1% reduction), revealed by computed tomography. Accordingly, underwent radical hysterectomy, there have no signs recurrence. Thus, combination suggested be useful for cervical adenocarcinoma.

参考文章(18)
Shaker R. Dakhil, Patsy Gacrama, Evelyne M Loyer, Rebecca Fueger, John J. Kavanagh, Ralph S. Freedman, Rodger Winn, Jadwiga Rusinkiewicz, Creighton L. Edwards, Andrzej P. Kudelka, Harvey Greenberg, Gordon Downey, Activity of paclitaxel in advanced or recurrent squamous cell cancer of the cervix. Clinical Cancer Research. ,vol. 2, pp. 1285- 1288 ,(1996)
John P. Curtin, John A. Blessing, Kenneth D. Webster, Peter G. Rose, Allan R. Mayer, Wesley C. Fowler, John H. Malfetano, Ronald D. Alvarez, Paclitaxel, an Active Agent in Nonsquamous Carcinomas of the Uterine Cervix: A Gynecologic Oncology Group Study Journal of Clinical Oncology. ,vol. 19, pp. 1275- 1278 ,(2001) , 10.1200/JCO.2001.19.5.1275
J J Kavanagh, D Gershenson, L Copeland, W S Roberts, Combination chemotherapy for metastatic or recurrent adenocarcinoma of the cervix. Journal of Clinical Oncology. ,vol. 5, pp. 1621- 1623 ,(1987) , 10.1200/JCO.1987.5.10.1621
Tsunehisa Kaku, Toshiharu Kamura, Toshiyuki Shigematsu, Kunihiro Sakai, Naoyuki Nakanami, Kenji Uehira, Satoshi Amada, Hiroaki Kobayashi, Toshiaki Saito, Hitoo Nakano, Adenocarcinoma of the uterine cervix with predominantly villogladular papillary growth pattern. Gynecologic Oncology. ,vol. 64, pp. 147- 152 ,(1997) , 10.1006/GYNO.1996.4539
Peter J. Moberg, Nina Einhorn, Claes Silfverswärd, Gunnar Söderberg, Adenocarcinoma of the uterine cervix Cancer. ,vol. 57, pp. 407- 410 ,(1986) , 10.1002/1097-0142(19860115)57:2<407::AID-CNCR2820570239>3.0.CO;2-2
Lila Hopson, Michael A. Jones, Charles R. Boyce, Hector M. Tarraza, Papillary villoglandular carcinoma of the cervix. Gynecologic Oncology. ,vol. 39, pp. 221- 224 ,(1990) , 10.1016/0090-8258(90)90437-P
Guillermo Focaccia, Guillermo Suttora, Mirna Scenna, Jos?? M. Boughen, Bernardo A. Leone, Carlos T. Vallejo, Mario R. Machiavelli, Juan E. P??rez, Alberto O. Romero, Fabrina Bologna, Hern??n Vicente, Juan A. Lacava, Eduardo H. Ortiz, Alberto Cubero, Docetaxel as neoadjuvant chemotherapy in patients with advanced cervical carcinoma. American Journal of Clinical Oncology. ,vol. 26, pp. 477- 482 ,(2003) , 10.1097/01.COC.0000037109.12434.52
Yao S. Fu, James W. Reagan, J. G. Hsiu, John P. Storaasli, W. Budd Wentz, Adenocarcinoma and mixed carcinoma of the uterine cervix: I. A clinicopathologic study Cancer. ,vol. 49, pp. 2560- 2570 ,(1982) , 10.1002/1097-0142(19820615)49:12<2560::AID-CNCR2820491225>3.0.CO;2-G
M.Steven Piver, Sharad A. Ghamande, Gamal H. Eltabbakh, Catherine O'Neill-Coppola, First-line chemotherapy with paclitaxel and platinum for advanced and recurrent cancer of the cervix--a phase II study. Gynecologic Oncology. ,vol. 75, pp. 334- 337 ,(1999) , 10.1006/GYNO.1999.5586