What risk of death would people take to be cured of HIV and why? A survey of people living with HIV.

作者: Benjamin R. Murray , Allison Kratka , Karen A. Scherr , Nir Eyal , Jennifer Blumenthal-Barby

DOI: 10.1016/S2055-6640(20)30052-2

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摘要: Abstract People living with HIV (PLWHIV) can reasonably expect near-normal longevity, yet many express a willingness to assume significant risks be cured. We surveyed 200 PLWHIV who were stable on antiretroviral therapy (ART) quantify associations between the benefits they anticipate from cure and their risk tolerance for curative treatments. Sixty-five per cent expected health improve if cured of HIV, 41% predicted virus would stop responding medications over next 20 years 54% experiencing serious medication side effects in years. Respondents’ death varied widely (median 10%, 75th percentile 50%). In multivariate analyses, was associated long-term ART, greater financial resources being employed (all P

参考文章(35)
Rachel S. Lee, Arlene Kochman, Kathleen J. Sikkema, Internalized Stigma Among People Living with HIV-AIDS Aids and Behavior. ,vol. 6, pp. 309- 319 ,(2002) , 10.1023/A:1021144511957
Kathleen A. Ethier, Michael R. Rodriguez, Rachel A. Fox-Tierney, Chloe Martin, Gerald Friedland, Jeannette R. Ickovics, Recruitment in AIDS Clinical Trials: Investigation of Sociodemographic and Psychosocial Factors Affecting Participation in Clinical Research Aids and Behavior. ,vol. 3, pp. 219- 230 ,(1999) , 10.1023/A:1025456527845
A Gafni, The standard gamble method: what is being measured and how it is interpreted. Health Services Research. ,vol. 29, pp. 207- 224 ,(1994)
George W. Torrance, Utility approach to measuring health-related quality of life Journal of Chronic Diseases. ,vol. 40, pp. 593- 600 ,(1987) , 10.1016/0021-9681(87)90019-1
Yuan Dong, Xiaoxing Shen, Ruizhang Guo, Baochi Liu, Lingyan Zhu, Jing Wang, Linxia Zhang, Jun Sun, Xiaoyan Zhang, Jianqing Xu, Willingness to Participate in HIV Therapeutic Vaccine Trials among HIV-Infected Patients on ART in China PLoS ONE. ,vol. 9, pp. e111321- ,(2014) , 10.1371/JOURNAL.PONE.0111321
Mandy Garber, Barbara H. Hanusa, Galen E. Switzer, John Mellors, Robert M. Arnold, HIV-Infected African Americans are Willing to Participate in HIV Treatment Trials Journal of General Internal Medicine. ,vol. 22, pp. 17- 42 ,(2007) , 10.1007/S11606-007-0121-8
Kathryn I. Pollak, Robert Arnold, Stewart C. Alexander, Amy S. Jeffreys, Maren K. Olsen, Amy P. Abernethy, Keri L. Rodriguez, James A. Tulsky, Do patient attributes predict oncologist empathic responses and patient perceptions of empathy Supportive Care in Cancer. ,vol. 18, pp. 1405- 1411 ,(2010) , 10.1007/S00520-009-0762-8
Steven Woloshin, Lisa M. Schwartz, Megan Moncur, Sherine Gabriel, Anna N. A. Tosteson, Assessing values for health: numeracy matters. Medical Decision Making. ,vol. 21, pp. 382- 390 ,(2001) , 10.1177/0272989X0102100505
Alison J. Rodger, Rebecca Lodwick, Mauro Schechter, Steven Deeks, Janaki Amin, Richard Gilson, Roger Paredes, Elzbieta Bakowska, Frederik N. Engsig, Andrew Phillips, Mortality in well controlled HIV in the continuous antiretroviral therapy arms of the SMART and ESPRIT trials compared with the general population. AIDS. ,vol. 27, pp. 973- 979 ,(2013) , 10.1097/QAD.0B013E32835CAE9C