作者: Zhonghua Liu , Zhiqiang Ning , Hailin Lu , Tinghua Cao , Feng Zhou
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摘要: Long non-coding RNAs (lncRNAs) are functional components of the human genome. Recent studies have demonstrated that lncRNAs play essential roles in tumorigenesis, and involved cell proliferation, apoptosis, migration invasion several types tumor, including lung cancer. However, clinical relevance lncRNA expression cancer remains unknown. The aim present study was to investigate pattern RFPL3 antisense (RFPL3S) its associations with clinicopathological characteristics patients Whether RFPL3S can act as a potential prognostic biomarker for also investigated. tumor samples cells assessed using Oncomine database Cancer Cell Line Encyclopedia, respectively. Based on Kaplan-Meier Plotter analyses, values were further evaluated. It revealed highly expressed tissues when compared normal significantly associated pN factor, pTNM stage Ki-67 labeling index. In survival increased poor inversely first progression all patients. These results indicate may be significance