Nuclear magnetic resonance studies of some biologically active dihydropterins

作者: Takeshi Fukushima , Miki Akino

DOI: 10.1016/0003-9861(68)90002-7

关键词:

摘要: Abstract An improved isolation method for biopterin and neopterin from natural sources is described. Crystalline dihydrobiopterin dihydroneopterin were prepared by reduction with sodium dithionite successive purification column chromatography. The 7,8-dihydro structure of was established comparing their nuclear magnetic resonance (NMR) spectra to those authentic 7,8-dihydropteridines. NMR spectrum sepiapterin revealed that this compound also has the configuration.

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