Toxoplasma gondii infection in schizophrenia and associated clinical features

摘要: The belief that latent toxoplasmosis is asymptomatic has been questioned, in particular due to the repeated highlighted link between Toxoplasma gondii infection and an increased incidence of schizophrenia. However, understand this relationship, effect with on severity schizophrenia poorly studied. Our work focused comparing prevalence schizophrenic patients healthy controls, as well clinical features demographic characteristics Toxoplasma-seronegative Toxoplasma-seropositive rate IgG antibody was 74.8% compared 53.8% controls. Patients had a significantly higher mean serum antibodies T. seropositive male age disease onset, BPRS score, greater negative PANSS score lower GAF than seronegative patients. These results suggest symptoms This study provides further evidence hypothesis exposure may be risk factor for Moreover, men lead more severe cognitive less favorable course