Resection of single brain metastasis in non-small-cell lung cancer: Prognostic factors

摘要: Abstract Combined resection of primary non-small-cell lung cancer and single brain metastasis is reportedly superior to other treatments in prolonging survival disease-free interval. To identify prognostic factors that influenced we reviewed clinical records follow-up data 52 consecutive patients with who had been evaluated for combined operation: 19 synchronous 33 metachronous metastasis. Seven were excluded from operation because either early relapse after craniotomy or localization deep structures. Forty-one the 45 underwent complete remission neurologic symptoms. Actuarial 5-year second surgical intervention was 16% (median months, range 1 104 months). N0 status lobectomy only variables associated longer survival. survivals presentation 6.6% 19%, respectively. In length significantly status, lobectomy, interval between equal than 14.5 months. The subset operations months a 61% None N1-2 disease shorter alive at 20 These indicate may help subsets markedly different outcomes operation. (J Thorac Cardiovasc Surg 1996;112:146-53)