Blood pressure during pregnancy in Canadian Inuit: community differences related to diet

摘要: OBJECTIVE: To assess a possible relation between the incidence of hypertension during pregnancy and consumption fatty acids found in fish sea mammals. DESIGN: Retrospective survey pregnancy-induced hypertension; prospective diet survey. SETTING: Inuit women from seven communities Keewatin region Northwest Territories. PATIENTS: All Arviat (formerly Eskimo Point), Baker Lake, Chesterfield Inlet, Coral Harbour, Repulse Bay, Sanikiluaq Whale Cove who gave birth Sept. 1, 1984, Aug. 31, 1987. MAIN OUTCOME MEASURES: blood pressure measurements recorded pregnancy, communities, harvest country food (food obtained land or rather than bought store) for six self-reported fish, mammals terrestrial by subgroup subjects levels phospholipid cord serum samples infants. RESULTS: Significantly lower mean diastolic values last 6 hours were noted three with higher (78.2 [95% confidence limits (CL) 76.6 79.9] mm Hg) those four such (81.5 CL 80.1 82.9] (p less 0.005). The community type was independent other factors. Correspondingly, marine 2.6 times more likely to be hypertensive 0.007). Parity 0.05) prepregnancy weight 0.005) also significantly associated however, remained significant logistic regression analysis (odds ratio 2.56, p = 0.03). differences groups substantiated results survey, eicosapentaenoic acid (EPA) phospholipids data. CONCLUSIONS: Increased may beneficial at risk pregnancy. A randomized trial EPA supplementation is warranted.