Genomic reorganization in the concolor gibbon (Hylobates concolor) revealed by chromosome painting.

摘要: We employed fluorescence in situ hybridization (FISH) of specific DNA libraries all human chromosomes to establish homologies between the karyotype and Hylobates concolor (2n = 52). Numerous intra- interchromosomal rearrangements have led a massive reorganization H. concolor. There been minimum 31 translocations. The 25 autosomes are composed 63-67 recognizable segments that show homology regions 22 autosomes. Only 1 autosome, homologous chromosome 21, has not involved compared gene mapping data for with our found most cases these confirmed by results. presents case primate closely related humans, which morphology synteny highly disturbed manner similar encountered rodents.