Relevance of sensitivity testings (MIC) of S. aureus to predict the antibacterial action in milk.

摘要: Summary Bacterial susceptibility testings were carried out in parallel Iso-sensitest broth (ISB) and bovine milk cultures using 16 antibacterials 4 sensitive strains of mastitic isolates Staphylococcus aureus. Bacterial activities analyzed by continuous turbidity monitoring (broth cultures), fluorometric the resazurin-reducing redox activity, analyzing triphenyltetra-zolium (TTC)-reducing capacity at end incubation period. To obtain an equipotent bacteria-suppressing required general several times more antibiotic than respective ISB cultures. Antibacterial sulfadoxine-trimethoprim, vancomycin, novobiocin, macrolides, aminoglycosides oxytetracycline most effectively suppressed milk. Aminoglycosides suffered additionally from reduction oxygen environment. The s-lactams (penicillin G, oxacillin, cephalothin, ceftiofur, ampicillin, ampicillin-clavulanic acid), gentamicin enrofloxacin showed extremely variable sensitivity results depending on S. aureus/milk combination.