Redox Regulation of Cell Adhesion Processes

摘要: This chapter discusses the role of oxidants and antioxidants in regulation cell adhesion processes as well molecular mechanisms such regulation. Cell play a major immune functions other vital biological processes, embryogenesis, growth, differentiation, wound repair. adhesion, which is multistep process including rolling, firm attachment, transmigration leukocytes, mediated by several classes molecules. molecule expression adhesive properties cells are modified greatly diseased conditions involving redox imbalances, cancer, atherosclerosis, diabetes, chronic inflammation, ischemiareperfusion injury. Several stimuli cytokines, chemokines, phorbol ester known to activate function Both these evidences indicate that overall regulated—direct activation inhibitory action on function.