Restrictive antibiotherapy after renal transplantation

摘要: Forty-two patients were followed up after 44 renal transplantations in an effort to evaluate possible benefits from the following protocol: systematic microbiologic and clinical surveillance, early aggressive research for cause of suspected infections, refusal use prophylactic antibiotherapy, selection treatment according established infection. During 18,030 days follow-up 124 infections recorded, which 110 bacterial, 11 viral 3 protozoal. Eighty originated urinary tract, 17 skin wounds 10 lower respiratory tract. Septicemia occurred three times, one death due infection was recorded. In bacterial received antibiotics 2486 days. Ampicillin (given 816 days) "minor" drugs such as sulfonamides antiseptics 1036 used 74.5% time, whereas gentamicin only 2.6% time (64 days). Combined antibacterial therapy needed 1.2% (29 A restrictive policy regarding anti-biotherapy seems be beneficial transplant recipients.