Outcome of anatomic ganglionated plexi ablation to treat paroxysmal atrial fibrillation: a 3-year follow-up study.

摘要: Aims A new strategy for anatomically based ganglionated plexi (GP) ablation the treatment of paroxysmal atrial fibrillation (AF) has been proposed recently. We aimed to assess long-term outcome patients undergoing anatomic GP AF, in comparison with circumferential pulmonary vein (PV) isolation. Methods and results The study population consisted 70 (mean age 56.6 ± 10.9 years; 41 males) AF no history structural heart disease: 35 subjects underwent ablation, while consecutive had PV isolation (CPVI) (control group). groups were not different demographic clinical parameters. Anatomic required more points (85.6 5.5 vs. 74.4 6.2, P < 0.05) equal duration total procedure fluoroscopy times. During a mean follow-up period 36.3 2.3 months, freedom from any tachyarrhythmia without antiarrhythmics was achieved 34.3% after 65.7% CPVI (log-rank test = 0.008). Early arrhythmia recurrences independent predictors late recurrence [HR 6.44 (CI 95%; 3.14–13.18; 0.001) HR 2.08 1.03–4.22; 0.04), respectively]. Six group subsequent CPVI, plus peri-mitral flutter two them, further episodes five patients. Conclusion yields significantly lower success rate over period, when compared CPVI. Recurrences include macro re-entrant tachycardias.