Crucial Role of Vitamin D in the Musculoskeletal System

摘要: Vitamin D is well known to exert multiple functions in bone biology, autoimmune diseases, cell growth, inflammation or neuromuscular and other immune functions. It a fat-soluble vitamin present many foods. can be endogenously produced by ultraviolet rays from sunlight when the skin exposed initiate synthesis. However, since biologically inert obtained sun exposure diet, it must first activated human beings before functioning. The kidney liver play here crucial role hydroxylation of 25-hydroxyvitamin 1,25-dihydroxyvitamin kidney. In past decades, has been proven that deficiency involved diseases. Due D's central musculoskeletal system consequently strong negative impact on health cases deficiency, our aim was underline its importance physiology summarizing recent findings correlation status rickets, osteomalacia, osteopenia, primary secondary osteoporosis as sarcopenia pain. While these diseases all positively correlate with there great controversy regarding appropriate supplementation both positive effects mineral density, pain incidence falls are reported.