The transcriptional network for mesenchymal transformation of brain tumours
作者： Maria Stella Carro , Wei Keat Lim , Mariano Javier Alvarez , Robert J. Bollo , Xudong Zhao
DOI: 10.1038/NATURE08712
关键词:
摘要: The inference of transcriptional networks that regulate transitions into physiological or pathological cellular states remains a central challenge in systems biology. A mesenchymal …
harvard.edu
utsystem.edu
nature.com
stanford.edu 参考文章(53)
Hiroko Ohgaki, Paul Kleihues, Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas. Journal of Neuropathology and Experimental Neurology. ,vol. 64, pp. 479- 489 ,(2005) , 10.1093/JNEN/64.6.479
Annie Paquin, Fanie Barnabé-Heider, Ryoichiro Kageyama, Freda D Miller, CCAAT/Enhancer-Binding Protein Phosphorylation Biases Cortical Precursors to Generate Neurons Rather Than Astrocytes In Vivo The Journal of Neuroscience. ,vol. 25, pp. 10747- 10758 ,(2005) , 10.1523/JNEUROSCI.2662-05.2005
Kinichi Nakashima, Makoto Yanagisawa, Hirokazu Arakawa, Naoki Kimura, Tatsuhiro Hisatsune, Masahiro Kawabata, Kohei Miyazono, Tetsuya Taga, Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300. Science. ,vol. 284, pp. 479- 482 ,(1999) , 10.1126/SCIENCE.284.5413.479
Xudong Zhao, Julian Ik-Tsen Heng, Daniele Guardavaccaro, Richeng Jiang, Michele Pagano, Francois Guillemot, Antonio Iavarone, Anna Lasorella, The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein. Nature Cell Biology. ,vol. 10, pp. 643- 653 ,(2008) , 10.1038/NCB1727
J. Tegner, M. K. S. Yeung, J. Hasty, J. J. Collins, Reverse engineering gene networks: Integrating genetic perturbations with dynamical modeling Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 5944- 5949 ,(2003) , 10.1073/PNAS.0933416100
François Fuks, Wendy A Burgers, Nadia Godin, Masataka Kasai, Tony Kouzarides, Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription The EMBO Journal. ,vol. 20, pp. 2536- 2544 ,(2001) , 10.1093/EMBOJ/20.10.2536
David Hanauer, Daniel Rhodes, Chandan Sinha-Kumar, Arul Chinnaiyan, Bioinformatics Approaches in the Study of Cancer Current Molecular Medicine. ,vol. 7, pp. 133- 141 ,(2007) , 10.2174/156652407779940431
Esta Sterneck, Peter F. Johnson, CCAAT/Enhancer Binding Protein β Is a Neuronal Transcriptional Regulator Activated by Nerve Growth Factor Receptor Signaling Journal of Neurochemistry. ,vol. 70, pp. 2424- 2433 ,(2002) , 10.1046/J.1471-4159.1998.70062424.X
Xudong Zhao, Domenico D' Arca, Wei Keat Lim, Manisha Brahmachary, Maria Stella Carro, Thomas Ludwig, Carlos Cordon Cardo, Francois Guillemot, Ken Aldape, Andrea Califano, Antonio Iavarone, Anna Lasorella, The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain Developmental Cell. ,vol. 17, pp. 210- 221 ,(2009) , 10.1016/J.DEVCEL.2009.07.009
Andrew E Wurmser, Kinichi Nakashima, Robert G Summers, Nicolas Toni, Kevin A D'amour, Dieter C Lie, Fred H Gage, None, Cell fusion-independent differentiation of neural stem cells to the endothelial lineage Nature. ,vol. 430, pp. 350- 356 ,(2004) , 10.1038/NATURE02604