Developing strategies for long term follow up of survivors of childhood cancer

摘要: The treatment of childhood cancer has been increasingly successful over the past 30 years. Most paediatric cancers are now curable with multiagent chemotherapy in combination surgery and radiotherapy. overall survival five years after diagnosis is 70% for all malignancies. incidence low (1200-1300 children affected each year Britain), but sustained improvement number long term survivors increasing—about 850 additional year. With this improved survival, it important to increase our knowledge any costs form physical psychosocial adverse health outcomes. This review looks at evidence relating clinical follow up considers ways develop such future. An awareness possible complications not only optimising care current also modifying future protocols avoid therapies that associated unacceptable morbidity or mortality. We have summarised on selected complications; inevitably based retrospective studies. In final section we discuss development a strategy survivors. #### Summary points Long strategies needed because increasing numbers cancers Models need be developed formally evaluated Increasing may medical problems will require ongoing specialist up The role, training programmes, career structure late effects nurse practitioner needs developed The primary physician an role up There prospective evaluation new treatments randomised studies interventions resolve substantial uncertainties …